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Job

Principle Research Associate, Drug Product Process Science

  • Job ref:

    8756

  • Location:

    Cambridge, United States

  • Sector:

    Pharmaceutical

  • Job type:

    Contract

  • Contact:

    Nicholas Haun

  • Published:

    about 1 year ago

Senior/Principal Research Associate, Drug Product Process Science

Contract

Cambridge, MA

The Role:
  • We seek a skilled and motivated scientist to work in a tight-knit team developing mRNA formulations and scaled processes. The selected candidate will contribute to a portfolio of scientific initiatives with the goal of elucidating fundamental principles behind the assembly, purification, and stabilization of mRNA delivery systems. We seek applicants that are proactive, enthusiastic, and show a passion for science. Applicants should have exceptional time management and communications skills with strengths in experimental design and execution. Previous experience with lipid nanoparticles (LNPs), tangential flow filtration, and chemical/biophysical characterization of nanoparticles is preferred. The position will support cross-functional teams across CMC, Research and Development, Production, and Drug Product Analytical Development

Here’s What You’ll Do:

  • Design and execute experiments that advance fundamental understanding of mRNA lipid nanoparticle synthesis and stabilization.
  • Evaluate and scale existing and novel process modes.
  • Characterize nanoparticle physicochemical properties through collaboration with the Drug Product Analytical team.
  • Analyze, interpret, and document experimental data and communicate outcomes to the Drug Product team and stakeholders.
  • Collect and share relevant academic literature, leverage external consultants/SMEs, and establish new collaborations with internal groups.

Here’s What You’ll Bring to the Table:

  • BS in Chemical Engineering, Chemistry, Pharmaceutical Science or related field with 2-5 years or MS with 0-2 years of industry experience in Pharmaceutical or Biotechnology development.
  • Experience in the development of nanoparticle products and processes.
    • Preferred: experience with lipid nanoparticle (LNP) preparation and optimization. Experience with tangential flow filtration.
  • Experience with chemical and biophysical characterization tools for drug delivery systems.
  • Motivated, detail oriented, and shows a passion for science.
  • Comfortable working in a dynamic environment.
  • Flexible, adaptable in collaborations.
  • Ability to manage multiple projects and communicate progress and challenges.
  • Driven to complete assignments.